Tramodol Hcl
Tramodol Hcl Brand names, Tramodol Hcl Analogs
Tramodol Hcl Brand Names Mixture
- No information avaliable
Tramodol Hcl Chemical_Formula
C16H25NO2
Tramodol Hcl RX_link
http://www.rxlist.com/cgi/generic/tramadol.htm
Tramodol Hcl fda sheet
Tramodol Hcl msds (material safety sheet)
Tramodol Hcl Synthesis Reference
K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)
Tramodol Hcl Molecular Weight
263.375 g/mol
Tramodol Hcl Melting Point
180-181oC
Tramodol Hcl H2O Solubility
Soluble in water.
Tramodol Hcl State
Solid
Tramodol Hcl LogP
2.951
Tramodol Hcl Dosage Forms
Tablet
Tramodol Hcl Indication
Indicated in the treatment of moderate to severe pain.
Tramodol Hcl Pharmacology
Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.
Tramodol Hcl Absorption
Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.
Tramodol Hcl side effects and Toxicity
LD50=350mg/kg (orally in mice)
Tramodol Hcl Patient Information
No information avaliable
Tramodol Hcl Organisms Affected
Humans and other mammals
