Terbutaline en es it fr

Terbutaline Brand names, Terbutaline Analogs

Terbutaline Brand Names Mixture

  • No information avaliable

Terbutaline Chemical_Formula


Terbutaline RX_link


Terbutaline fda sheet

Terbutaline msds (material safety sheet)

Terbutaline MSDS

Terbutaline Synthesis Reference

K. Wetterlin, L. A. Svensson, Belg. pat. 704,932; eidem, U.S. pat. 3,937,838 (1968, 1976 both to Draco)

Terbutaline Molecular Weight

225.284 g/mol

Terbutaline Melting Point

119-122 oC

Terbutaline H2O Solubility

213 mg/mL

Terbutaline State


Terbutaline LogP


Terbutaline Dosage Forms

Metered-dose (aerosol); Powder; Tablets; IV injection; Subcutaneous injection

Terbutaline Indication

For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Terbutaline Pharmacology

Terbutaline is a relatively selective beta2-adrenergic bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, including terbutaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Terbutaline Absorption

No information avaliable

Terbutaline side effects and Toxicity

Terbutaline Sulfate: Oral LD50(rat) = 8.7 g/kg; Oral LD50(mouse) = 205 mg/kg; Oral LD50(dog) = 1.5 g/kg; IP LD50(rat)= 220 mg/kg ; IP LD50(mouse) = 130 mg/kg; Oral LD50(rabbit) = >8 g/kg; IV LD50(mouse) = 36 mg/kg; IV LD50(dog) = 116 mg/kg; IV LD50(rabbit) = 110 mg/kg

Terbutaline Patient Information

Terbutaline Organisms Affected

Humans and other mammals