Terbutaline Sulfate en es it fr

Terbutaline Sulfate Brand names, Terbutaline Sulfate Analogs

Terbutaline Sulfate Brand Names Mixture

  • No information avaliable

Terbutaline Sulfate Chemical_Formula

C12H19NO3

Terbutaline Sulfate RX_link

http://www.rxlist.com/cgi/generic3/terbutaline.htm

Terbutaline Sulfate fda sheet

Terbutaline Sulfate msds (material safety sheet)

Terbutaline_Sulfate MSDS

Terbutaline Sulfate Synthesis Reference

K. Wetterlin, L. A. Svensson, Belg. pat. 704,932; eidem, U.S. pat. 3,937,838 (1968, 1976 both to Draco)

Terbutaline Sulfate Molecular Weight

225.284 g/mol

Terbutaline Sulfate Melting Point

119-122 oC

Terbutaline Sulfate H2O Solubility

213 mg/mL

Terbutaline Sulfate State

Solid

Terbutaline Sulfate LogP

1.567

Terbutaline Sulfate Dosage Forms

Metered-dose (aerosol); Powder; Tablets; IV injection; Subcutaneous injection

Terbutaline Sulfate Indication

For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Terbutaline Sulfate Pharmacology

Terbutaline is a relatively selective beta2-adrenergic bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, including terbutaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Terbutaline Sulfate Absorption

No information avaliable

Terbutaline Sulfate side effects and Toxicity

Terbutaline Sulfate: Oral LD50(rat) = 8.7 g/kg; Oral LD50(mouse) = 205 mg/kg; Oral LD50(dog) = 1.5 g/kg; IP LD50(rat)= 220 mg/kg ; IP LD50(mouse) = 130 mg/kg; Oral LD50(rabbit) = >8 g/kg; IV LD50(mouse) = 36 mg/kg; IV LD50(dog) = 116 mg/kg; IV LD50(rabbit) = 110 mg/kg

Terbutaline Sulfate Patient Information

Terbutaline Sulfate Organisms Affected

Humans and other mammals