Terbutalin en es it fr

Terbutalin Brand names, Terbutalin Analogs

Terbutalin Brand Names Mixture

  • No information avaliable

Terbutalin Chemical_Formula

C12H19NO3

Terbutalin RX_link

http://www.rxlist.com/cgi/generic3/terbutaline.htm

Terbutalin fda sheet

Terbutalin msds (material safety sheet)

Terbutalin MSDS

Terbutalin Synthesis Reference

K. Wetterlin, L. A. Svensson, Belg. pat. 704,932; eidem, U.S. pat. 3,937,838 (1968, 1976 both to Draco)

Terbutalin Molecular Weight

225.284 g/mol

Terbutalin Melting Point

119-122 oC

Terbutalin H2O Solubility

213 mg/mL

Terbutalin State

Solid

Terbutalin LogP

1.567

Terbutalin Dosage Forms

Metered-dose (aerosol); Powder; Tablets; IV injection; Subcutaneous injection

Terbutalin Indication

For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Terbutalin Pharmacology

Terbutaline is a relatively selective beta2-adrenergic bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, including terbutaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Terbutalin Absorption

No information avaliable

Terbutalin side effects and Toxicity

Terbutaline Sulfate: Oral LD50(rat) = 8.7 g/kg; Oral LD50(mouse) = 205 mg/kg; Oral LD50(dog) = 1.5 g/kg; IP LD50(rat)= 220 mg/kg ; IP LD50(mouse) = 130 mg/kg; Oral LD50(rabbit) = >8 g/kg; IV LD50(mouse) = 36 mg/kg; IV LD50(dog) = 116 mg/kg; IV LD50(rabbit) = 110 mg/kg

Terbutalin Patient Information

Terbutalin Organisms Affected

Humans and other mammals