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Bricanyl Brand names, Bricanyl Analogs

Bricanyl Brand Names Mixture

  • No information avaliable

Bricanyl Chemical_Formula

C12H19NO3

Bricanyl RX_link

http://www.rxlist.com/cgi/generic3/terbutaline.htm

Bricanyl fda sheet

Bricanyl msds (material safety sheet)

Bricanyl MSDS

Bricanyl Synthesis Reference

K. Wetterlin, L. A. Svensson, Belg. pat. 704,932; eidem, U.S. pat. 3,937,838 (1968, 1976 both to Draco)

Bricanyl Molecular Weight

225.284 g/mol

Bricanyl Melting Point

119-122 oC

Bricanyl H2O Solubility

213 mg/mL

Bricanyl State

Solid

Bricanyl LogP

1.567

Bricanyl Dosage Forms

Metered-dose (aerosol); Powder; Tablets; IV injection; Subcutaneous injection

Bricanyl Indication

For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Bricanyl Pharmacology

Terbutaline is a relatively selective beta2-adrenergic bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, including terbutaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Bricanyl Absorption

No information avaliable

Bricanyl side effects and Toxicity

Terbutaline Sulfate: Oral LD50(rat) = 8.7 g/kg; Oral LD50(mouse) = 205 mg/kg; Oral LD50(dog) = 1.5 g/kg; IP LD50(rat)= 220 mg/kg ; IP LD50(mouse) = 130 mg/kg; Oral LD50(rabbit) = >8 g/kg; IV LD50(mouse) = 36 mg/kg; IV LD50(dog) = 116 mg/kg; IV LD50(rabbit) = 110 mg/kg

Bricanyl Patient Information

Bricanyl Organisms Affected

Humans and other mammals