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Bricaril Brand names, Bricaril Analogs

Bricaril Brand Names Mixture

  • No information avaliable

Bricaril Chemical_Formula

C12H19NO3

Bricaril RX_link

http://www.rxlist.com/cgi/generic3/terbutaline.htm

Bricaril fda sheet

Bricaril msds (material safety sheet)

Bricaril MSDS

Bricaril Synthesis Reference

K. Wetterlin, L. A. Svensson, Belg. pat. 704,932; eidem, U.S. pat. 3,937,838 (1968, 1976 both to Draco)

Bricaril Molecular Weight

225.284 g/mol

Bricaril Melting Point

119-122 oC

Bricaril H2O Solubility

213 mg/mL

Bricaril State

Solid

Bricaril LogP

1.567

Bricaril Dosage Forms

Metered-dose (aerosol); Powder; Tablets; IV injection; Subcutaneous injection

Bricaril Indication

For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Bricaril Pharmacology

Terbutaline is a relatively selective beta2-adrenergic bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, including terbutaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Bricaril Absorption

No information avaliable

Bricaril side effects and Toxicity

Terbutaline Sulfate: Oral LD50(rat) = 8.7 g/kg; Oral LD50(mouse) = 205 mg/kg; Oral LD50(dog) = 1.5 g/kg; IP LD50(rat)= 220 mg/kg ; IP LD50(mouse) = 130 mg/kg; Oral LD50(rabbit) = >8 g/kg; IV LD50(mouse) = 36 mg/kg; IV LD50(dog) = 116 mg/kg; IV LD50(rabbit) = 110 mg/kg

Bricaril Patient Information

Bricaril Organisms Affected

Humans and other mammals