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Brethaire Brand names, Brethaire Analogs

Brethaire Brand Names Mixture

  • No information avaliable

Brethaire Chemical_Formula


Brethaire RX_link

Brethaire fda sheet

Brethaire msds (material safety sheet)

Brethaire MSDS

Brethaire Synthesis Reference

K. Wetterlin, L. A. Svensson, Belg. pat. 704,932; eidem, U.S. pat. 3,937,838 (1968, 1976 both to Draco)

Brethaire Molecular Weight

225.284 g/mol

Brethaire Melting Point

119-122 oC

Brethaire H2O Solubility

213 mg/mL

Brethaire State


Brethaire LogP


Brethaire Dosage Forms

Metered-dose (aerosol); Powder; Tablets; IV injection; Subcutaneous injection

Brethaire Indication

For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Brethaire Pharmacology

Terbutaline is a relatively selective beta2-adrenergic bronchodilator. The pharmacologic effects of beta adrenergic agonist drugs, including terbutaline, are at least in part attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic- 3',5'- adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

Brethaire Absorption

No information avaliable

Brethaire side effects and Toxicity

Terbutaline Sulfate: Oral LD50(rat) = 8.7 g/kg; Oral LD50(mouse) = 205 mg/kg; Oral LD50(dog) = 1.5 g/kg; IP LD50(rat)= 220 mg/kg ; IP LD50(mouse) = 130 mg/kg; Oral LD50(rabbit) = >8 g/kg; IV LD50(mouse) = 36 mg/kg; IV LD50(dog) = 116 mg/kg; IV LD50(rabbit) = 110 mg/kg

Brethaire Patient Information

Brethaire Organisms Affected

Humans and other mammals