Sal seidlitense
Brand names,
Sal seidlitense
Analogs
Sal seidlitense
Brand Names Mixture
Sal seidlitense
Chemical_Formula
C43H68ClNO11
Sal seidlitense
RX_link
http://www.rxlist.com/cgi/generic/elidel.htm
Sal seidlitense
fda sheet
Sal seidlitense
msds (material safety sheet)
Sal seidlitense
Synthesis Reference
No information avaliable
Sal seidlitense
Molecular Weight
810.453 g/mol
Sal seidlitense
Melting Point
No information avaliable
Sal seidlitense
H2O Solubility
No information avaliable
Sal seidlitense
State
Solid
Sal seidlitense
LogP
5.099
Sal seidlitense
Dosage Forms
Cream
Sal seidlitense
Indication
For treatment of mild to moderate atopic dermatitis.
Sal seidlitense
Pharmacology
Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune system by various environmental or emotional triggers. Scientists do not know exactly how pimecrolimus reduces the manifestations of atopic dermatitis, but pimecrolimus reduces the action of T-cells and mast cells which are part of the immune system and contribute to responses of the immune system. Pimecrolimus prevents the activation of T-cells by blocking the effects of chemicals (cytokines) released by the body that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation.
Sal seidlitense
Absorption
Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, Cmax, half-life, etc. cannot be reliably done.
Sal seidlitense
side effects and Toxicity
Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.
Sal seidlitense
Patient Information
Sal seidlitense
Organisms Affected
Humans and other mammals