Sal anglicum
Brand names,
Sal anglicum
Analogs
Sal anglicum
Brand Names Mixture
Sal anglicum
Chemical_Formula
C43H68ClNO11
Sal anglicum
RX_link
http://www.rxlist.com/cgi/generic/elidel.htm
Sal anglicum
fda sheet
Sal anglicum
msds (material safety sheet)
Sal anglicum
Synthesis Reference
No information avaliable
Sal anglicum
Molecular Weight
810.453 g/mol
Sal anglicum
Melting Point
No information avaliable
Sal anglicum
H2O Solubility
No information avaliable
Sal anglicum
State
Solid
Sal anglicum
LogP
5.099
Sal anglicum
Dosage Forms
Cream
Sal anglicum
Indication
For treatment of mild to moderate atopic dermatitis.
Sal anglicum
Pharmacology
Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune system by various environmental or emotional triggers. Scientists do not know exactly how pimecrolimus reduces the manifestations of atopic dermatitis, but pimecrolimus reduces the action of T-cells and mast cells which are part of the immune system and contribute to responses of the immune system. Pimecrolimus prevents the activation of T-cells by blocking the effects of chemicals (cytokines) released by the body that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation.
Sal anglicum
Absorption
Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, Cmax, half-life, etc. cannot be reliably done.
Sal anglicum
side effects and Toxicity
Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.
Sal anglicum
Patient Information
Sal anglicum
Organisms Affected
Humans and other mammals