Epsom salts
Brand names,
Epsom salts
Analogs
Epsom salts
Brand Names Mixture
Epsom salts
Chemical_Formula
C43H68ClNO11
Epsom salts
RX_link
http://www.rxlist.com/cgi/generic/elidel.htm
Epsom salts
fda sheet
Epsom salts
msds (material safety sheet)
Epsom salts
Synthesis Reference
No information avaliable
Epsom salts
Molecular Weight
810.453 g/mol
Epsom salts
Melting Point
No information avaliable
Epsom salts
H2O Solubility
No information avaliable
Epsom salts
State
Solid
Epsom salts
LogP
5.099
Epsom salts
Dosage Forms
Cream
Epsom salts
Indication
For treatment of mild to moderate atopic dermatitis.
Epsom salts
Pharmacology
Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune system by various environmental or emotional triggers. Scientists do not know exactly how pimecrolimus reduces the manifestations of atopic dermatitis, but pimecrolimus reduces the action of T-cells and mast cells which are part of the immune system and contribute to responses of the immune system. Pimecrolimus prevents the activation of T-cells by blocking the effects of chemicals (cytokines) released by the body that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation.
Epsom salts
Absorption
Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, Cmax, half-life, etc. cannot be reliably done.
Epsom salts
side effects and Toxicity
Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.
Epsom salts
Patient Information
Epsom salts
Organisms Affected
Humans and other mammals