Magnesium sulfate heptahydrate
Brand names,
Magnesium sulfate heptahydrate
Analogs
Magnesium sulfate heptahydrate
Brand Names Mixture
Magnesium sulfate heptahydrate
Chemical_Formula
C43H68ClNO11
Magnesium sulfate heptahydrate
RX_link
http://www.rxlist.com/cgi/generic/elidel.htm
Magnesium sulfate heptahydrate
fda sheet
Magnesium sulfate heptahydrate
msds (material safety sheet)
Magnesium sulfate heptahydrate
Synthesis Reference
No information avaliable
Magnesium sulfate heptahydrate
Molecular Weight
810.453 g/mol
Magnesium sulfate heptahydrate
Melting Point
No information avaliable
Magnesium sulfate heptahydrate
H2O Solubility
No information avaliable
Magnesium sulfate heptahydrate
State
Solid
Magnesium sulfate heptahydrate
LogP
5.099
Magnesium sulfate heptahydrate
Dosage Forms
Cream
Magnesium sulfate heptahydrate
Indication
For treatment of mild to moderate atopic dermatitis.
Magnesium sulfate heptahydrate
Pharmacology
Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune system by various environmental or emotional triggers. Scientists do not know exactly how pimecrolimus reduces the manifestations of atopic dermatitis, but pimecrolimus reduces the action of T-cells and mast cells which are part of the immune system and contribute to responses of the immune system. Pimecrolimus prevents the activation of T-cells by blocking the effects of chemicals (cytokines) released by the body that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation.
Magnesium sulfate heptahydrate
Absorption
Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, Cmax, half-life, etc. cannot be reliably done.
Magnesium sulfate heptahydrate
side effects and Toxicity
Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.
Magnesium sulfate heptahydrate
Patient Information
Magnesium sulfate heptahydrate
Organisms Affected
Humans and other mammals