Magnesium Sulphate Hydrate
Brand names,
Magnesium Sulphate Hydrate
Analogs
Magnesium Sulphate Hydrate
Brand Names Mixture
Magnesium Sulphate Hydrate
Chemical_Formula
C43H68ClNO11
Magnesium Sulphate Hydrate
RX_link
http://www.rxlist.com/cgi/generic/elidel.htm
Magnesium Sulphate Hydrate
fda sheet
Magnesium Sulphate Hydrate
msds (material safety sheet)
Magnesium Sulphate Hydrate
Synthesis Reference
No information avaliable
Magnesium Sulphate Hydrate
Molecular Weight
810.453 g/mol
Magnesium Sulphate Hydrate
Melting Point
No information avaliable
Magnesium Sulphate Hydrate
H2O Solubility
No information avaliable
Magnesium Sulphate Hydrate
State
Solid
Magnesium Sulphate Hydrate
LogP
5.099
Magnesium Sulphate Hydrate
Dosage Forms
Cream
Magnesium Sulphate Hydrate
Indication
For treatment of mild to moderate atopic dermatitis.
Magnesium Sulphate Hydrate
Pharmacology
Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune system by various environmental or emotional triggers. Scientists do not know exactly how pimecrolimus reduces the manifestations of atopic dermatitis, but pimecrolimus reduces the action of T-cells and mast cells which are part of the immune system and contribute to responses of the immune system. Pimecrolimus prevents the activation of T-cells by blocking the effects of chemicals (cytokines) released by the body that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation.
Magnesium Sulphate Hydrate
Absorption
Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, Cmax, half-life, etc. cannot be reliably done.
Magnesium Sulphate Hydrate
side effects and Toxicity
Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.
Magnesium Sulphate Hydrate
Patient Information
Magnesium Sulphate Hydrate
Organisms Affected
Humans and other mammals