Bitter salt
Brand names,
Bitter salt
Analogs
Bitter salt
Brand Names Mixture
Bitter salt
Chemical_Formula
C43H68ClNO11
Bitter salt
RX_link
http://www.rxlist.com/cgi/generic/elidel.htm
Bitter salt
fda sheet
Bitter salt
msds (material safety sheet)
Bitter salt
Synthesis Reference
No information avaliable
Bitter salt
Molecular Weight
810.453 g/mol
Bitter salt
Melting Point
No information avaliable
Bitter salt
H2O Solubility
No information avaliable
Bitter salt
State
Solid
Bitter salt
LogP
5.099
Bitter salt
Dosage Forms
Cream
Bitter salt
Indication
For treatment of mild to moderate atopic dermatitis.
Bitter salt
Pharmacology
Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune system by various environmental or emotional triggers. Scientists do not know exactly how pimecrolimus reduces the manifestations of atopic dermatitis, but pimecrolimus reduces the action of T-cells and mast cells which are part of the immune system and contribute to responses of the immune system. Pimecrolimus prevents the activation of T-cells by blocking the effects of chemicals (cytokines) released by the body that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation.
Bitter salt
Absorption
Because of the low systemic absorption of pimecrolimus following topical application the calculation of standard pharmacokinetic measures such as AUC, Cmax, half-life, etc. cannot be reliably done.
Bitter salt
side effects and Toxicity
Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.
Bitter salt
Patient Information
Bitter salt
Organisms Affected
Humans and other mammals