Phenoxybenzamine Hydrochloride
Phenoxybenzamine Hydrochloride Brand names, Phenoxybenzamine Hydrochloride Analogs
Phenoxybenzamine Hydrochloride Brand Names Mixture
- No information avaliable
Phenoxybenzamine Hydrochloride Chemical_Formula
C18H22ClNO
Phenoxybenzamine Hydrochloride RX_link
http://www.rxlist.com/cgi/generic3/phenoxybenz.htm
Phenoxybenzamine Hydrochloride fda sheet
Phenoxybenzamine Hydrochloride msds (material safety sheet)
Phenoxybenzamine Hydrochloride Synthesis Reference
No information avaliable
Phenoxybenzamine Hydrochloride Molecular Weight
303.826 g/mol
Phenoxybenzamine Hydrochloride Melting Point
39 oC
Phenoxybenzamine Hydrochloride H2O Solubility
No information avaliable
Phenoxybenzamine Hydrochloride State
Solid
Phenoxybenzamine Hydrochloride LogP
4.601
Phenoxybenzamine Hydrochloride Dosage Forms
No information avaliable
Phenoxybenzamine Hydrochloride Indication
For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Phenoxybenzamine Hydrochloride Pharmacology
Phenoxybenzamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phenoxybenzamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phenoxybenzamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phenoxybenzamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.
Phenoxybenzamine Hydrochloride Absorption
No information avaliable
Phenoxybenzamine Hydrochloride side effects and Toxicity
No information avaliable
Phenoxybenzamine Hydrochloride Patient Information
No information avaliable
Phenoxybenzamine Hydrochloride Organisms Affected
Humans and other mammals
