Dibenzylene
Brand names,
Dibenzylene
Analogs
Dibenzylene
Brand Names Mixture
Dibenzylene
Chemical_Formula
C18H22ClNO
Dibenzylene
RX_link
http://www.rxlist.com/cgi/generic3/phenoxybenz.htm
Dibenzylene
fda sheet
Dibenzylene
msds (material safety sheet)
Dibenzylene
Synthesis Reference
No information avaliable
Dibenzylene
Molecular Weight
303.826 g/mol
Dibenzylene
Melting Point
39 oC
Dibenzylene
H2O Solubility
No information avaliable
Dibenzylene
State
Solid
Dibenzylene
LogP
4.601
Dibenzylene
Dosage Forms
No information avaliable
Dibenzylene
Indication
For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Dibenzylene
Pharmacology
Phenoxybenzamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phenoxybenzamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phenoxybenzamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phenoxybenzamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.
Dibenzylene
Absorption
No information avaliable
Dibenzylene
side effects and Toxicity
No information avaliable
Dibenzylene
Patient Information
No information avaliable
Dibenzylene
Organisms Affected
Humans and other mammals