Phenyoxybenzaminehydrochloride
Phenyoxybenzaminehydrochloride Brand names, Phenyoxybenzaminehydrochloride Analogs
Phenyoxybenzaminehydrochloride Brand Names Mixture
- No information avaliable
Phenyoxybenzaminehydrochloride Chemical_Formula
C18H22ClNO
Phenyoxybenzaminehydrochloride RX_link
http://www.rxlist.com/cgi/generic3/phenoxybenz.htm
Phenyoxybenzaminehydrochloride fda sheet
Phenyoxybenzaminehydrochloride msds (material safety sheet)
Phenyoxybenzaminehydrochloride Synthesis Reference
No information avaliable
Phenyoxybenzaminehydrochloride Molecular Weight
303.826 g/mol
Phenyoxybenzaminehydrochloride Melting Point
39 oC
Phenyoxybenzaminehydrochloride H2O Solubility
No information avaliable
Phenyoxybenzaminehydrochloride State
Solid
Phenyoxybenzaminehydrochloride LogP
4.601
Phenyoxybenzaminehydrochloride Dosage Forms
No information avaliable
Phenyoxybenzaminehydrochloride Indication
For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Phenyoxybenzaminehydrochloride Pharmacology
Phenoxybenzamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phenoxybenzamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phenoxybenzamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phenoxybenzamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.
Phenyoxybenzaminehydrochloride Absorption
No information avaliable
Phenyoxybenzaminehydrochloride side effects and Toxicity
No information avaliable
Phenyoxybenzaminehydrochloride Patient Information
No information avaliable
Phenyoxybenzaminehydrochloride Organisms Affected
Humans and other mammals
