Phenoxybenzamine
Phenoxybenzamine Brand names, Phenoxybenzamine Analogs
Phenoxybenzamine Brand Names Mixture
- No information avaliable
Phenoxybenzamine Chemical_Formula
C18H22ClNO
Phenoxybenzamine RX_link
http://www.rxlist.com/cgi/generic3/phenoxybenz.htm
Phenoxybenzamine fda sheet
Phenoxybenzamine msds (material safety sheet)
Phenoxybenzamine Synthesis Reference
No information avaliable
Phenoxybenzamine Molecular Weight
303.826 g/mol
Phenoxybenzamine Melting Point
39 oC
Phenoxybenzamine H2O Solubility
No information avaliable
Phenoxybenzamine State
Solid
Phenoxybenzamine LogP
4.601
Phenoxybenzamine Dosage Forms
No information avaliable
Phenoxybenzamine Indication
For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Phenoxybenzamine Pharmacology
Phenoxybenzamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phenoxybenzamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phenoxybenzamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phenoxybenzamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.
Phenoxybenzamine Absorption
No information avaliable
Phenoxybenzamine side effects and Toxicity
No information avaliable
Phenoxybenzamine Patient Information
No information avaliable
Phenoxybenzamine Organisms Affected
Humans and other mammals
