ANTIBIOTIC BB-K8
ANTIBIOTIC BB-K8 Brand names, ANTIBIOTIC BB-K8 Analogs
ANTIBIOTIC BB-K8 Brand Names Mixture
- No information avaliable
ANTIBIOTIC BB-K8 Chemical_Formula
C22H43N5O13
ANTIBIOTIC BB-K8 RX_link
http://www.rxlist.com/cgi/generic3/amikacin.htm
ANTIBIOTIC BB-K8 fda sheet
ANTIBIOTIC BB-K8 msds (material safety sheet)
ANTIBIOTIC BB-K8 Synthesis Reference
H. Kawaguchi, T. Naito, Ger. pat. 2,234,315; H. Kawaguchi et al., U.S. pat. 3,781,268 (both 1973 to Bristol-Myers)
ANTIBIOTIC BB-K8 Molecular Weight
585.603 g/mol
ANTIBIOTIC BB-K8 Melting Point
203-204 oC
ANTIBIOTIC BB-K8 H2O Solubility
1.85E+005 mg/L
ANTIBIOTIC BB-K8 State
Solid
ANTIBIOTIC BB-K8 LogP
-9.048
ANTIBIOTIC BB-K8 Dosage Forms
IM infusion; IM injection
ANTIBIOTIC BB-K8 Indication
For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species.
ANTIBIOTIC BB-K8 Pharmacology
Amikacin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
ANTIBIOTIC BB-K8 Absorption
Rapidly absorbed after intramuscular administration
ANTIBIOTIC BB-K8 side effects and Toxicity
No information avaliable
ANTIBIOTIC BB-K8 Patient Information
ANTIBIOTIC BB-K8 Organisms Affected
Enteric bacteria and other eubacteria
