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Briclin Brand names, Briclin Analogs

Briclin Brand Names Mixture

  • No information avaliable

Briclin Chemical_Formula


Briclin RX_link

Briclin fda sheet

Briclin msds (material safety sheet)

Briclin MSDS

Briclin Synthesis Reference

H. Kawaguchi, T. Naito, Ger. pat. 2,234,315; H. Kawaguchi et al., U.S. pat. 3,781,268 (both 1973 to Bristol-Myers)

Briclin Molecular Weight

585.603 g/mol

Briclin Melting Point

203-204 oC

Briclin H2O Solubility

1.85E+005 mg/L

Briclin State


Briclin LogP


Briclin Dosage Forms

IM infusion; IM injection

Briclin Indication

For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species.

Briclin Pharmacology

Amikacin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.

Briclin Absorption

Rapidly absorbed after intramuscular administration

Briclin side effects and Toxicity

No information avaliable

Briclin Patient Information

Briclin Organisms Affected

Enteric bacteria and other eubacteria