Amikavet
Amikavet Brand names, Amikavet Analogs
Amikavet Brand Names Mixture
- No information avaliable
Amikavet Chemical_Formula
C22H43N5O13
Amikavet RX_link
http://www.rxlist.com/cgi/generic3/amikacin.htm
Amikavet fda sheet
Amikavet msds (material safety sheet)
Amikavet Synthesis Reference
H. Kawaguchi, T. Naito, Ger. pat. 2,234,315; H. Kawaguchi et al., U.S. pat. 3,781,268 (both 1973 to Bristol-Myers)
Amikavet Molecular Weight
585.603 g/mol
Amikavet Melting Point
203-204 oC
Amikavet H2O Solubility
1.85E+005 mg/L
Amikavet State
Solid
Amikavet LogP
-9.048
Amikavet Dosage Forms
IM infusion; IM injection
Amikavet Indication
For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species.
Amikavet Pharmacology
Amikacin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Amikavet Absorption
Rapidly absorbed after intramuscular administration
Amikavet side effects and Toxicity
No information avaliable
Amikavet Patient Information
Amikavet Organisms Affected
Enteric bacteria and other eubacteria
