Amikacin Base en es it fr

Amikacin Base Brand names, Amikacin Base Analogs

Amikacin Base Brand Names Mixture

  • No information avaliable

Amikacin Base Chemical_Formula


Amikacin Base RX_link

Amikacin Base fda sheet

Amikacin Base msds (material safety sheet)

Amikacin_Base MSDS

Amikacin Base Synthesis Reference

H. Kawaguchi, T. Naito, Ger. pat. 2,234,315; H. Kawaguchi et al., U.S. pat. 3,781,268 (both 1973 to Bristol-Myers)

Amikacin Base Molecular Weight

585.603 g/mol

Amikacin Base Melting Point

203-204 oC

Amikacin Base H2O Solubility

1.85E+005 mg/L

Amikacin Base State


Amikacin Base LogP


Amikacin Base Dosage Forms

IM infusion; IM injection

Amikacin Base Indication

For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species.

Amikacin Base Pharmacology

Amikacin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.

Amikacin Base Absorption

Rapidly absorbed after intramuscular administration

Amikacin Base side effects and Toxicity

No information avaliable

Amikacin Base Patient Information

Amikacin Base Organisms Affected

Enteric bacteria and other eubacteria