PharmacyCodes



Nitrendipinum [Inn-Latin] en es it fr

Nitrendipinum [Inn-Latin] Brand names, Nitrendipinum [Inn-Latin] Analogs

Nitrendipinum [Inn-Latin] Brand Names Mixture

  • No information avaliable

Nitrendipinum [Inn-Latin] Chemical_Formula

C18H20N2O6

Nitrendipinum [Inn-Latin] RX_link

No information avaliable

Nitrendipinum [Inn-Latin] fda sheet

Nitrendipinum [Inn-Latin] msds (material safety sheet)

Nitrendipinum [Inn-Latin] Synthesis Reference

H. Meyar et al., Ger. pat 2117571; eidem, US pat. 3799934

Nitrendipinum [Inn-Latin] Molecular Weight

360.361 g/mol

Nitrendipinum [Inn-Latin] Melting Point

156-160 oC

Nitrendipinum [Inn-Latin] H2O Solubility

Insoluble

Nitrendipinum [Inn-Latin] State

Solid

Nitrendipinum [Inn-Latin] LogP

2.756

Nitrendipinum [Inn-Latin] Dosage Forms

No information avaliable

Nitrendipinum [Inn-Latin] Indication

For the treatment of mild to moderate hypertension

Nitrendipinum [Inn-Latin] Pharmacology

Nitrendipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nitrendipine is similar to other peripheral vasodilators. Nitrendipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Nitrendipinum [Inn-Latin] Absorption

No information avaliable

Nitrendipinum [Inn-Latin] side effects and Toxicity

No information avaliable

Nitrendipinum [Inn-Latin] Patient Information

No information avaliable

Nitrendipinum [Inn-Latin] Organisms Affected

Humans and other mammals