Deiten
Deiten Brand names, Deiten Analogs
Deiten Brand Names Mixture
- No information avaliable
Deiten Chemical_Formula
C18H20N2O6
Deiten RX_link
No information avaliable
Deiten fda sheet
Deiten msds (material safety sheet)
Deiten Synthesis Reference
H. Meyar et al., Ger. pat 2117571; eidem, US pat. 3799934
Deiten Molecular Weight
360.361 g/mol
Deiten Melting Point
156-160 oC
Deiten H2O Solubility
Insoluble
Deiten State
Solid
Deiten LogP
2.756
Deiten Dosage Forms
No information avaliable
Deiten Indication
For the treatment of mild to moderate hypertension
Deiten Pharmacology
Nitrendipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nitrendipine is similar to other peripheral vasodilators. Nitrendipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Deiten Absorption
No information avaliable
Deiten side effects and Toxicity
No information avaliable
Deiten Patient Information
No information avaliable
Deiten Organisms Affected
Humans and other mammals
