Bayotensin
Brand names,
Bayotensin
Analogs
Bayotensin
Brand Names Mixture
Bayotensin
Chemical_Formula
C18H20N2O6
Bayotensin
RX_link
No information avaliable
Bayotensin
fda sheet
Bayotensin
msds (material safety sheet)
Bayotensin
Synthesis Reference
H. Meyar et al., Ger. pat 2117571; eidem, US pat. 3799934
Bayotensin
Molecular Weight
360.361 g/mol
Bayotensin
Melting Point
156-160 oC
Bayotensin
H2O Solubility
Insoluble
Bayotensin
State
Solid
Bayotensin
LogP
2.756
Bayotensin
Dosage Forms
No information avaliable
Bayotensin
Indication
For the treatment of mild to moderate hypertension
Bayotensin
Pharmacology
Nitrendipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nitrendipine is similar to other peripheral vasodilators. Nitrendipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Bayotensin
Absorption
No information avaliable
Bayotensin
side effects and Toxicity
No information avaliable
Bayotensin
Patient Information
No information avaliable
Bayotensin
Organisms Affected
Humans and other mammals