Bylotensin
Bylotensin Brand names, Bylotensin Analogs
Bylotensin Brand Names Mixture
- No information avaliable
Bylotensin Chemical_Formula
C18H20N2O6
Bylotensin RX_link
No information avaliable
Bylotensin fda sheet
Bylotensin msds (material safety sheet)
Bylotensin Synthesis Reference
H. Meyar et al., Ger. pat 2117571; eidem, US pat. 3799934
Bylotensin Molecular Weight
360.361 g/mol
Bylotensin Melting Point
156-160 oC
Bylotensin H2O Solubility
Insoluble
Bylotensin State
Solid
Bylotensin LogP
2.756
Bylotensin Dosage Forms
No information avaliable
Bylotensin Indication
For the treatment of mild to moderate hypertension
Bylotensin Pharmacology
Nitrendipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nitrendipine is similar to other peripheral vasodilators. Nitrendipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
Bylotensin Absorption
No information avaliable
Bylotensin side effects and Toxicity
No information avaliable
Bylotensin Patient Information
No information avaliable
Bylotensin Organisms Affected
Humans and other mammals
