Metixene hydrochloride
Metixene hydrochloride Brand names, Metixene hydrochloride Analogs
Metixene hydrochloride Brand Names Mixture
- No information avaliable
Metixene hydrochloride Chemical_Formula
C16H16ClN3O3S
Metixene hydrochloride RX_link
http://www.rxlist.com/cgi/generic2/metolazone.htm
Metixene hydrochloride fda sheet
Metixene hydrochloride msds (material safety sheet)
Metixene hydrochloride Synthesis Reference
No information avaliable
Metixene hydrochloride Molecular Weight
365.835 g/mol
Metixene hydrochloride Melting Point
256 oC
Metixene hydrochloride H2O Solubility
60.3 mg/L
Metixene hydrochloride State
Solid
Metixene hydrochloride LogP
2.784
Metixene hydrochloride Dosage Forms
Tablet for oral administration (0.5mg)
Metixene hydrochloride Indication
For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.
Metixene hydrochloride Pharmacology
Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. A proximal action of metolazone has been shown in humans by increased excretion of phosphate and magnesium ions and by a markedly increased fractional excretion of sodium in patients with severely compromised glomerular filtration. This action has been demonstrated in animals by micropuncture studies.
Metixene hydrochloride Absorption
Peak blood levels are obtained within 2 to 4 hours of oral administration.
Metixene hydrochloride side effects and Toxicity
Symptoms of overdose include difficulty breathing, dizziness, dizziness on standing up, drowsiness, fainting, irritation of the stomach and intestines, and lethargy leading to coma.
Metixene hydrochloride Patient Information
No information avaliable
Metixene hydrochloride Organisms Affected
Humans and other mammals
