Methixart

Methixart Brand names, Methixart Analogs

Methixart Brand Names Mixture

No information avaliable

Methixart Chemical_Formula

C₁₆H₁₆ClN₃O₃S

Methixart RX_link

http://www.rxlist.com/cgi/generic2/metolazone.htm

Methixart fda sheet

Methixart FDA

Methixart msds (material safety sheet)

Methixart Synthesis Reference

No information avaliable

Methixart Molecular Weight

365.835 g/mol

Methixart Melting Point

256 ^oC

Methixart H₂O Solubility

60.3 mg/L

Methixart State

Solid

Methixart LogP

2.784

Methixart Dosage Forms

Tablet for oral administration (0.5mg)

Methixart Indication

For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.

Methixart Pharmacology

Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. A proximal action of metolazone has been shown in humans by increased excretion of phosphate and magnesium ions and by a markedly increased fractional excretion of sodium in patients with severely compromised glomerular filtration. This action has been demonstrated in animals by micropuncture studies.

Methixart Absorption

Peak blood levels are obtained within 2 to 4 hours of oral administration.

Methixart side effects and Toxicity

Symptoms of overdose include difficulty breathing, dizziness, dizziness on standing up, drowsiness, fainting, irritation of the stomach and intestines, and lethargy leading to coma.

Methixart Patient Information