Methixene

Methixene Brand names, Methixene Analogs

Methixene Brand Names Mixture

No information avaliable

Methixene Chemical_Formula

C₁₆H₁₆ClN₃O₃S

Methixene RX_link

http://www.rxlist.com/cgi/generic2/metolazone.htm

Methixene fda sheet

Methixene FDA

Methixene msds (material safety sheet)

Methixene Synthesis Reference

No information avaliable

Methixene Molecular Weight

365.835 g/mol

Methixene Melting Point

256 ^oC

Methixene H₂O Solubility

60.3 mg/L

Methixene State

Solid

Methixene LogP

2.784

Methixene Dosage Forms

Tablet for oral administration (0.5mg)

Methixene Indication

For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.

Methixene Pharmacology

Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. A proximal action of metolazone has been shown in humans by increased excretion of phosphate and magnesium ions and by a markedly increased fractional excretion of sodium in patients with severely compromised glomerular filtration. This action has been demonstrated in animals by micropuncture studies.

Methixene Absorption

Peak blood levels are obtained within 2 to 4 hours of oral administration.

Methixene side effects and Toxicity

Symptoms of overdose include difficulty breathing, dizziness, dizziness on standing up, drowsiness, fainting, irritation of the stomach and intestines, and lethargy leading to coma.

Methixene Patient Information