Methixen

Methixen Brand names, Methixen Analogs

Methixen Brand Names Mixture

No information avaliable

Methixen Chemical_Formula

C₁₆H₁₆ClN₃O₃S

Methixen RX_link

http://www.rxlist.com/cgi/generic2/metolazone.htm

Methixen fda sheet

Methixen FDA

Methixen msds (material safety sheet)

Methixen Synthesis Reference

No information avaliable

Methixen Molecular Weight

365.835 g/mol

Methixen Melting Point

256 ^oC

Methixen H₂O Solubility

60.3 mg/L

Methixen State

Solid

Methixen LogP

2.784

Methixen Dosage Forms

Tablet for oral administration (0.5mg)

Methixen Indication

For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.

Methixen Pharmacology

Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. A proximal action of metolazone has been shown in humans by increased excretion of phosphate and magnesium ions and by a markedly increased fractional excretion of sodium in patients with severely compromised glomerular filtration. This action has been demonstrated in animals by micropuncture studies.

Methixen Absorption

Peak blood levels are obtained within 2 to 4 hours of oral administration.

Methixen side effects and Toxicity

Symptoms of overdose include difficulty breathing, dizziness, dizziness on standing up, drowsiness, fainting, irritation of the stomach and intestines, and lethargy leading to coma.

Methixen Patient Information