Lisinopril
Brand names,
Lisinopril
Analogs
Lisinopril
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Lisinopril
Chemical_Formula
C21H31N3O5
Lisinopril
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Lisinopril
fda sheet
Lisinopril
msds (material safety sheet)
Lisinopril
Synthesis Reference
No information avaliable
Lisinopril
Molecular Weight
405.488 g/mol
Lisinopril
Melting Point
No information avaliable
Lisinopril
H2O Solubility
13 mg/L
Lisinopril
State
Solid
Lisinopril
LogP
-1.22
Lisinopril
Dosage Forms
Tablet
Lisinopril
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Lisinopril
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Lisinopril
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Lisinopril
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Lisinopril
Patient Information
Lisinopril
Organisms Affected
Humans and other mammals