Zestril
Brand names,
Zestril
Analogs
Zestril
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Zestril
Chemical_Formula
C21H31N3O5
Zestril
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Zestril
fda sheet
Zestril
msds (material safety sheet)
Zestril
Synthesis Reference
No information avaliable
Zestril
Molecular Weight
405.488 g/mol
Zestril
Melting Point
No information avaliable
Zestril
H2O Solubility
13 mg/L
Zestril
State
Solid
Zestril
LogP
-1.22
Zestril
Dosage Forms
Tablet
Zestril
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Zestril
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Zestril
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Zestril
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Zestril
Patient Information
Zestril
Organisms Affected
Humans and other mammals