Inhibril
Brand names,
Inhibril
Analogs
Inhibril
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Inhibril
Chemical_Formula
C21H31N3O5
Inhibril
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Inhibril
fda sheet
Inhibril
msds (material safety sheet)
Inhibril
Synthesis Reference
No information avaliable
Inhibril
Molecular Weight
405.488 g/mol
Inhibril
Melting Point
No information avaliable
Inhibril
H2O Solubility
13 mg/L
Inhibril
State
Solid
Inhibril
LogP
-1.22
Inhibril
Dosage Forms
Tablet
Inhibril
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Inhibril
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Inhibril
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Inhibril
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Inhibril
Patient Information
Inhibril
Organisms Affected
Humans and other mammals