Lysinopril
Brand names,
Lysinopril
Analogs
Lysinopril
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Lysinopril
Chemical_Formula
C21H31N3O5
Lysinopril
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Lysinopril
fda sheet
Lysinopril
msds (material safety sheet)
Lysinopril
Synthesis Reference
No information avaliable
Lysinopril
Molecular Weight
405.488 g/mol
Lysinopril
Melting Point
No information avaliable
Lysinopril
H2O Solubility
13 mg/L
Lysinopril
State
Solid
Lysinopril
LogP
-1.22
Lysinopril
Dosage Forms
Tablet
Lysinopril
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Lysinopril
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Lysinopril
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Lysinopril
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Lysinopril
Patient Information
Lysinopril
Organisms Affected
Humans and other mammals