Lisipril
Brand names,
Lisipril
Analogs
Lisipril
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Lisipril
Chemical_Formula
C21H31N3O5
Lisipril
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Lisipril
fda sheet
Lisipril
msds (material safety sheet)
Lisipril
Synthesis Reference
No information avaliable
Lisipril
Molecular Weight
405.488 g/mol
Lisipril
Melting Point
No information avaliable
Lisipril
H2O Solubility
13 mg/L
Lisipril
State
Solid
Lisipril
LogP
-1.22
Lisipril
Dosage Forms
Tablet
Lisipril
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Lisipril
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Lisipril
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Lisipril
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Lisipril
Patient Information
Lisipril
Organisms Affected
Humans and other mammals