Sinopril
Brand names,
Sinopril
Analogs
Sinopril
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Sinopril
Chemical_Formula
C21H31N3O5
Sinopril
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Sinopril
fda sheet
Sinopril
msds (material safety sheet)
Sinopril
Synthesis Reference
No information avaliable
Sinopril
Molecular Weight
405.488 g/mol
Sinopril
Melting Point
No information avaliable
Sinopril
H2O Solubility
13 mg/L
Sinopril
State
Solid
Sinopril
LogP
-1.22
Sinopril
Dosage Forms
Tablet
Sinopril
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Sinopril
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Sinopril
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Sinopril
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Sinopril
Patient Information
Sinopril
Organisms Affected
Humans and other mammals