Zestoretic
Brand names,
Zestoretic
Analogs
Zestoretic
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Zestoretic
Chemical_Formula
C21H31N3O5
Zestoretic
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Zestoretic
fda sheet
Zestoretic
msds (material safety sheet)
Zestoretic
Synthesis Reference
No information avaliable
Zestoretic
Molecular Weight
405.488 g/mol
Zestoretic
Melting Point
No information avaliable
Zestoretic
H2O Solubility
13 mg/L
Zestoretic
State
Solid
Zestoretic
LogP
-1.22
Zestoretic
Dosage Forms
Tablet
Zestoretic
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Zestoretic
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Zestoretic
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Zestoretic
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Zestoretic
Patient Information
Zestoretic
Organisms Affected
Humans and other mammals