Linopril
Brand names,
Linopril
Analogs
Linopril
Brand Names Mixture
- Prinzide (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 10/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/12.5mg (Hydrochlorothiazide + Lisinopril)
- Zestoretic Tab 20/25mg (Hydrochlorothiazide + Lisinopril)
Linopril
Chemical_Formula
C21H31N3O5
Linopril
RX_link
http://www.rxlist.com/cgi/generic/lisinop.htm
Linopril
fda sheet
Linopril
msds (material safety sheet)
Linopril
Synthesis Reference
No information avaliable
Linopril
Molecular Weight
405.488 g/mol
Linopril
Melting Point
No information avaliable
Linopril
H2O Solubility
13 mg/L
Linopril
State
Solid
Linopril
LogP
-1.22
Linopril
Dosage Forms
Tablet
Linopril
Indication
For the treatment of hypertension, heart failure and acute myocardial infarction. It may be used alone or in combination with thiazide diuretics
Linopril
Pharmacology
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure (CHF), postmyocardial infarction, and diabetic nephropathy or retinopathy. Although it is the lysine ester of enalaprilat, the active form of the prodrug enalapril, lisinopril is active unchanged.
Linopril
Absorption
Approximately 25%, but widely variable between individuals (6 to 60%)
Linopril
side effects and Toxicity
hypotension, LD50= 2000 mg/kg(orally in rat)
Linopril
Patient Information
Linopril
Organisms Affected
Humans and other mammals