PharmacyCodes



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Heptovir Brand names, Heptovir Analogs

Heptovir Brand Names Mixture

  • Combivir (Lamivudine + Zidovudine)
  • Kivexa (Abacavir (Abacavir Sulfate) + Lamivudine)
  • Trizivir (Abacavir (Abacavir Sulfate) + Lamivudine + Zidovudine)

Heptovir Chemical_Formula

C8H11N3O3S

Heptovir RX_link

http://www.rxlist.com/cgi/generic3/lamivudine.htm

Heptovir fda sheet

Heptovir FDA

Heptovir msds (material safety sheet)

Heptovir MSDS

Heptovir Synthesis Reference

No information avaliable

Heptovir Molecular Weight

229.257 g/mol

Heptovir Melting Point

160-162 oC

Heptovir H2O Solubility

70 mg/ml

Heptovir State

Solid

Heptovir LogP

No information avaliable

Heptovir Dosage Forms

Solution; Tablet

Heptovir Indication

For the treatment of HIV infection and chronic hepatitis B (HBV).

Heptovir Pharmacology

Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). Lamivudine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

Heptovir Absorption

Lamivudine was rapidly absorbed after oral administration in HIV-infected patients. Absolute bioavailability in adults is 86% ± 16% for the tablet and 87% ± 13% for the oral solution.

Heptovir side effects and Toxicity

No information avaliable

Heptovir Patient Information

Heptovir Organisms Affected

Human immunodeficiency virus and Hepatitis B virus