PharmacyCodes



Epivir-Hbv en es it fr

Epivir-Hbv Brand names, Epivir-Hbv Analogs

Epivir-Hbv Brand Names Mixture

  • Combivir (Lamivudine + Zidovudine)
  • Kivexa (Abacavir (Abacavir Sulfate) + Lamivudine)
  • Trizivir (Abacavir (Abacavir Sulfate) + Lamivudine + Zidovudine)

Epivir-Hbv Chemical_Formula

C8H11N3O3S

Epivir-Hbv RX_link

http://www.rxlist.com/cgi/generic3/lamivudine.htm

Epivir-Hbv fda sheet

Epivir-Hbv FDA

Epivir-Hbv msds (material safety sheet)

Epivir-Hbv MSDS

Epivir-Hbv Synthesis Reference

No information avaliable

Epivir-Hbv Molecular Weight

229.257 g/mol

Epivir-Hbv Melting Point

160-162 oC

Epivir-Hbv H2O Solubility

70 mg/ml

Epivir-Hbv State

Solid

Epivir-Hbv LogP

No information avaliable

Epivir-Hbv Dosage Forms

Solution; Tablet

Epivir-Hbv Indication

For the treatment of HIV infection and chronic hepatitis B (HBV).

Epivir-Hbv Pharmacology

Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). Lamivudine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

Epivir-Hbv Absorption

Lamivudine was rapidly absorbed after oral administration in HIV-infected patients. Absolute bioavailability in adults is 86% ± 16% for the tablet and 87% ± 13% for the oral solution.

Epivir-Hbv side effects and Toxicity

No information avaliable

Epivir-Hbv Patient Information

Epivir-Hbv Organisms Affected

Human immunodeficiency virus and Hepatitis B virus