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Trizivir Brand names, Trizivir Analogs

Trizivir Brand Names Mixture

  • Combivir (Lamivudine + Zidovudine)
  • Kivexa (Abacavir (Abacavir Sulfate) + Lamivudine)
  • Trizivir (Abacavir (Abacavir Sulfate) + Lamivudine + Zidovudine)

Trizivir Chemical_Formula

C8H11N3O3S

Trizivir RX_link

http://www.rxlist.com/cgi/generic3/lamivudine.htm

Trizivir fda sheet

Trizivir FDA

Trizivir msds (material safety sheet)

Trizivir MSDS

Trizivir Synthesis Reference

No information avaliable

Trizivir Molecular Weight

229.257 g/mol

Trizivir Melting Point

160-162 oC

Trizivir H2O Solubility

70 mg/ml

Trizivir State

Solid

Trizivir LogP

No information avaliable

Trizivir Dosage Forms

Solution; Tablet

Trizivir Indication

For the treatment of HIV infection and chronic hepatitis B (HBV).

Trizivir Pharmacology

Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). Lamivudine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

Trizivir Absorption

Lamivudine was rapidly absorbed after oral administration in HIV-infected patients. Absolute bioavailability in adults is 86% ± 16% for the tablet and 87% ± 13% for the oral solution.

Trizivir side effects and Toxicity

No information avaliable

Trizivir Patient Information

Trizivir Organisms Affected

Human immunodeficiency virus and Hepatitis B virus