Dextrometorphan
Brand names,
Dextrometorphan
Analogs
Dextrometorphan
Brand Names Mixture
Dextrometorphan
Chemical_Formula
C18H25NO
Dextrometorphan
RX_link
No information avaliable
Dextrometorphan
fda sheet
Dextrometorphan
msds (material safety sheet)
Dextrometorphan
Synthesis Reference
No information avaliable
Dextrometorphan
Molecular Weight
271.397 g/mol
Dextrometorphan
Melting Point
No information avaliable
Dextrometorphan
H2O Solubility
74.7 mg/L
Dextrometorphan
State
Solid
Dextrometorphan
LogP
4.323
Dextrometorphan
Dosage Forms
Capsule; Liquid; Lozenge; Syrup; Tablet
Dextrometorphan
Indication
For treatment and relief of dry cough.
Dextrometorphan
Pharmacology
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Dextrometorphan
Absorption
Rapidly absorbed from the gastrointestinal tract.
Dextrometorphan
side effects and Toxicity
No information avaliable
Dextrometorphan
Patient Information
No information avaliable
Dextrometorphan
Organisms Affected
Humans and other mammals