Dextromethorfan
Brand names,
Dextromethorfan
Analogs
Dextromethorfan
Brand Names Mixture
Dextromethorfan
Chemical_Formula
C18H25NO
Dextromethorfan
RX_link
No information avaliable
Dextromethorfan
fda sheet
Dextromethorfan
msds (material safety sheet)
Dextromethorfan
Synthesis Reference
No information avaliable
Dextromethorfan
Molecular Weight
271.397 g/mol
Dextromethorfan
Melting Point
No information avaliable
Dextromethorfan
H2O Solubility
74.7 mg/L
Dextromethorfan
State
Solid
Dextromethorfan
LogP
4.323
Dextromethorfan
Dosage Forms
Capsule; Liquid; Lozenge; Syrup; Tablet
Dextromethorfan
Indication
For treatment and relief of dry cough.
Dextromethorfan
Pharmacology
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Dextromethorfan
Absorption
Rapidly absorbed from the gastrointestinal tract.
Dextromethorfan
side effects and Toxicity
No information avaliable
Dextromethorfan
Patient Information
No information avaliable
Dextromethorfan
Organisms Affected
Humans and other mammals