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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C18H25NO
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
271.397 g/mol
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Melting Point
No information avaliable
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H2O Solubility
74.7 mg/L
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State
Solid
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LogP
4.323
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Dosage Forms
Capsule; Liquid; Lozenge; Syrup; Tablet
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Indication
For treatment and relief of dry cough.
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Pharmacology
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
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Absorption
Rapidly absorbed from the gastrointestinal tract.
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals