Methorphan
Brand names,
Methorphan
Analogs
Methorphan
Brand Names Mixture
Methorphan
Chemical_Formula
C18H25NO
Methorphan
RX_link
No information avaliable
Methorphan
fda sheet
Methorphan
msds (material safety sheet)
Methorphan
Synthesis Reference
No information avaliable
Methorphan
Molecular Weight
271.397 g/mol
Methorphan
Melting Point
No information avaliable
Methorphan
H2O Solubility
74.7 mg/L
Methorphan
State
Solid
Methorphan
LogP
4.323
Methorphan
Dosage Forms
Capsule; Liquid; Lozenge; Syrup; Tablet
Methorphan
Indication
For treatment and relief of dry cough.
Methorphan
Pharmacology
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Methorphan
Absorption
Rapidly absorbed from the gastrointestinal tract.
Methorphan
side effects and Toxicity
No information avaliable
Methorphan
Patient Information
No information avaliable
Methorphan
Organisms Affected
Humans and other mammals