Demorphan
Brand names,
Demorphan
Analogs
Demorphan
Brand Names Mixture
Demorphan
Chemical_Formula
C18H25NO
Demorphan
RX_link
No information avaliable
Demorphan
fda sheet
Demorphan
msds (material safety sheet)
Demorphan
Synthesis Reference
No information avaliable
Demorphan
Molecular Weight
271.397 g/mol
Demorphan
Melting Point
No information avaliable
Demorphan
H2O Solubility
74.7 mg/L
Demorphan
State
Solid
Demorphan
LogP
4.323
Demorphan
Dosage Forms
Capsule; Liquid; Lozenge; Syrup; Tablet
Demorphan
Indication
For treatment and relief of dry cough.
Demorphan
Pharmacology
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Demorphan
Absorption
Rapidly absorbed from the gastrointestinal tract.
Demorphan
side effects and Toxicity
No information avaliable
Demorphan
Patient Information
No information avaliable
Demorphan
Organisms Affected
Humans and other mammals