Koffex DM
Brand names,
Koffex DM
Analogs
Koffex DM
Brand Names Mixture
Koffex DM
Chemical_Formula
C18H25NO
Koffex DM
RX_link
No information avaliable
Koffex DM
fda sheet
Koffex DM
msds (material safety sheet)
Koffex DM
Synthesis Reference
No information avaliable
Koffex DM
Molecular Weight
271.397 g/mol
Koffex DM
Melting Point
No information avaliable
Koffex DM
H2O Solubility
74.7 mg/L
Koffex DM
State
Solid
Koffex DM
LogP
4.323
Koffex DM
Dosage Forms
Capsule; Liquid; Lozenge; Syrup; Tablet
Koffex DM
Indication
For treatment and relief of dry cough.
Koffex DM
Pharmacology
Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Koffex DM
Absorption
Rapidly absorbed from the gastrointestinal tract.
Koffex DM
side effects and Toxicity
No information avaliable
Koffex DM
Patient Information
No information avaliable
Koffex DM
Organisms Affected
Humans and other mammals