Dexrazoxane

Dexrazoxane Brand names, Dexrazoxane Analogs

Dexrazoxane Brand Names Mixture

No information avaliable

Dexrazoxane Chemical_Formula

C₁₁H₁₆N₄O₄

Dexrazoxane RX_link

http://www.rxlist.com/cgi/generic2/dexrazoxane.htm

Dexrazoxane fda sheet

Dexrazoxane FDA

Dexrazoxane msds (material safety sheet)

Dexrazoxane MSDS

Dexrazoxane Synthesis Reference

No information avaliable

Dexrazoxane Molecular Weight

268.269 g/mol

Dexrazoxane Melting Point

191 - 197 ^oC

Dexrazoxane H₂O Solubility

Sparingly soluble

Dexrazoxane State

Solid

Dexrazoxane LogP

-2.135

Dexrazoxane Dosage Forms

Liquid; Powder for solution

Dexrazoxane Indication

For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.

Dexrazoxane Pharmacology

Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.

Dexrazoxane Absorption

IV administration results in complete bioavailability.

Dexrazoxane side effects and Toxicity

Intraperitoneal, mouse LD₁₀ = 500 mg/kg. Intravenous, dog LD₁₀ = 2 gm/kg.

Dexrazoxane Patient Information