Razoxane
Razoxane Brand names, Razoxane Analogs
Razoxane Brand Names Mixture
- No information avaliable
Razoxane Chemical_Formula
C11H16N4O4
Razoxane RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Razoxane fda sheet
Razoxane msds (material safety sheet)
Razoxane Synthesis Reference
No information avaliable
Razoxane Molecular Weight
268.269 g/mol
Razoxane Melting Point
191 - 197 oC
Razoxane H2O Solubility
Sparingly soluble
Razoxane State
Solid
Razoxane LogP
-2.135
Razoxane Dosage Forms
Liquid; Powder for solution
Razoxane Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Razoxane Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Razoxane Absorption
IV administration results in complete bioavailability.
Razoxane side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Razoxane Patient Information
No information avaliable
Razoxane Organisms Affected
Humans and other mammals
