Troxozone

Troxozone Brand names, Troxozone Analogs

Troxozone Brand Names Mixture

No information avaliable

Troxozone Chemical_Formula

C₁₁H₁₆N₄O₄

Troxozone RX_link

http://www.rxlist.com/cgi/generic2/dexrazoxane.htm

Troxozone fda sheet

Troxozone FDA

Troxozone msds (material safety sheet)

Troxozone MSDS

Troxozone Synthesis Reference

No information avaliable

Troxozone Molecular Weight

268.269 g/mol

Troxozone Melting Point

191 - 197 ^oC

Troxozone H₂O Solubility

Sparingly soluble

Troxozone State

Solid

Troxozone LogP

-2.135

Troxozone Dosage Forms

Liquid; Powder for solution

Troxozone Indication

For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.

Troxozone Pharmacology

Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.

Troxozone Absorption

IV administration results in complete bioavailability.

Troxozone side effects and Toxicity

Intraperitoneal, mouse LD₁₀ = 500 mg/kg. Intravenous, dog LD₁₀ = 2 gm/kg.

Troxozone Patient Information