Razoxin

Razoxin Brand names, Razoxin Analogs

Razoxin Brand Names Mixture

No information avaliable

Razoxin Chemical_Formula

C₁₁H₁₆N₄O₄

Razoxin RX_link

http://www.rxlist.com/cgi/generic2/dexrazoxane.htm

Razoxin fda sheet

Razoxin FDA

Razoxin msds (material safety sheet)

Razoxin MSDS

Razoxin Synthesis Reference

No information avaliable

Razoxin Molecular Weight

268.269 g/mol

Razoxin Melting Point

191 - 197 ^oC

Razoxin H₂O Solubility

Sparingly soluble

Razoxin State

Solid

Razoxin LogP

-2.135

Razoxin Dosage Forms

Liquid; Powder for solution

Razoxin Indication

For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.

Razoxin Pharmacology

Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.

Razoxin Absorption

IV administration results in complete bioavailability.

Razoxin side effects and Toxicity

Intraperitoneal, mouse LD₁₀ = 500 mg/kg. Intravenous, dog LD₁₀ = 2 gm/kg.

Razoxin Patient Information